Isolation and identification of cissetin--a setin-like antibiotic with a novel cis-octalin ring fusion.

@article{Boros2003IsolationAI,
  title={Isolation and identification of cissetin--a setin-like antibiotic with a novel cis-octalin ring fusion.},
  author={Christie A. Boros and A. Dix and Barry Katz and Y. Vasina and C. Pearce},
  journal={The Journal of antibiotics},
  year={2003},
  volume={56 10},
  pages={
          862-5
        }
}
  • Christie A. Boros, A. Dix, +2 authors C. Pearce
  • Published 2003
  • Chemistry, Medicine
  • The Journal of antibiotics
  • activity against methicillin-resistant Staphylococcus aureus (MRSA), we have isolated three different setin antibiotics from several different fungi-the previously reported equisetin (2)1) and trichosetin (3),2) and a novel setin-like compound (1) from OSI 50185. Like the known setin antibiotics, cissetin (1) is active against several Grampositive organisms,2-5) but it is most notable for the atypical cis ring fusion in the octalin portion of the molecule. Cissetin (1) was isolated from OSI… CONTINUE READING
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