Isolation and identification of a new mutagen, 2-amino-4-hydroxy-methyl-3,8-dimethylimidazo[4,5-f]quinoxaline (4-CH2OH-8-MeIQx), from beef extract.

Abstract

By monitoring the mutagenicity to a new Salmonella tester strain, YG1024, which has a much higher level of O-acetyltransferase activity than S.typhimurium TA98, we found two new mutagenic compounds in bacteriological-grade beef extract. One of them (compound I), which had a similar UV spectrum to that of 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (4,8… (More)

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@article{Kim1994IsolationAI, title={Isolation and identification of a new mutagen, 2-amino-4-hydroxy-methyl-3,8-dimethylimidazo[4,5-f]quinoxaline (4-CH2OH-8-MeIQx), from beef extract.}, author={I. S. Kim and K. Wakabayashi and Ryoji Kurosaka and Ziro Yamaizumi and Fumihiro Jinno and Souchi Koyota and A. Tada and Haruhiko Nukaya and M. Takahashi and Tomoko Sugimura}, journal={Carcinogenesis}, year={1994}, volume={15 1}, pages={21-6} }