Isolation and identification of a cDNA clone of rat placental lactogen II.

@article{Duckworth1986IsolationAI,
  title={Isolation and identification of a cDNA clone of rat placental lactogen II.},
  author={Mary Lynn Duckworth and Kevin L. Kirk and Henry G. Friesen},
  journal={The Journal of biological chemistry},
  year={1986},
  volume={261 23},
  pages={10871-8}
}
The developing rat placenta expresses two placental lactogens at different stages of pregnancy: rat placental lactogen I from Days 11 to 13 of pregnancy and rat placental lactogen II (rPLII) from Day 12 to term. In this paper, we describe cDNA clones for rPLII, which have been isolated from a Day 18 rat placental cDNA library. The rPLII clones hybrid-select a mRNA which translates in vitro to a protein of 25,000 daltons. This protein is processed by dog pancreatic microsomes to a 22,000-dalton… CONTINUE READING