Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans.

@article{Horvitz1980IsolationAG,
  title={Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans.},
  author={H Robert Horvitz and John E. Sulston},
  journal={Genetics},
  year={1980},
  volume={96 2},
  pages={435-54}
}
Twenty-four mutants that alter the normally invariant post-embryonic cell lineages of the nematode Caenorhabditis elegans have been isolated and genetically characterized. In some of these mutants, cell divisions fail that occur in wild-type animals; in other mutants, cells divide that do not normally do so. The mutants differ in the specificities of their defects, so that it is possible to identify mutations that affect some cell lineages but not others. These mutants define 14 complementation… CONTINUE READING

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