Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk

@article{Schwab2008IsolationAF,
  title={Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk},
  author={Rich{\'a}rd Schwab and Rita Bussolari and Daisy Corvetta and Olesya Chayka and Giorgia Santilli and Jimmy M-M Kwok and Giovanna Ferrari-Amorotti and Gian Paolo Tonini and Licia Iacoviello and Roberta Bertorelle and Chiara Menin and Michael Hubank and Bruno Calabretta and Arturo Sala},
  journal={Oncogene},
  year={2008},
  volume={27},
  pages={2929-2933}
}
The B-MYB proto-oncogene is a transcription factor belonging to the MYB family that is frequently overexpressed or amplified in different types of human malignancies. While it is suspected that B-MYB plays a role in human cancer, there is still no direct evidence of its causative role. Looking for mutations of the B-MYB gene in human cell lines and primary… CONTINUE READING