Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I.

  title={Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I.},
  author={Ruthann Nichols},
  journal={Molecular and cellular neurosciences},
  volume={3 4},
The Drosophila drosulfakinin (dsk) gene encodes the cholecystokinin homologues drosulfakinin-I (DSK-I) and drosulfakinin-II (DSK-II). The naturally occurring DSKI peptide was isolated from an extract of adult flies and its sequence determined by automated Edman degradation and sequence-specific radioimmunoassay. The dsk cDNA is expressed during the larval, pupal, and adult stages of development and is an abundant adult head transcript. Sequence-specific DSK antibodies localized DSK expression… CONTINUE READING

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