Isolation and evaluation of target cells in glaucoma research: hormone receptors and drug responses.

Abstract

To investigate the actions of drugs and hormones which influence intraocular pressure (IOP), we have been measuring receptor binding characteristics and dose-response effects using individual target cells from the anterior segment. Similar methods have also permitted us to develop sensitive radio-receptor assays for glucocorticoids and beta adrenergic antagonists. These methods provide a means to obtain new and potentially useful information regarding the efficacy and specificity of ocular drug therapy.

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@article{Polansky1985IsolationAE, title={Isolation and evaluation of target cells in glaucoma research: hormone receptors and drug responses.}, author={Jon R. Polansky and Jorge A. Alvarado}, journal={Current eye research}, year={1985}, volume={4 3}, pages={267-79} }