Isolation and culture of adult human liver progenitor cells: in vitro differentiation to hepatocyte-like cells.

@article{Gerbalchaloin2010IsolationAC,
  title={Isolation and culture of adult human liver progenitor cells: in vitro differentiation to hepatocyte-like cells.},
  author={Sabine Gerbal-chaloin and C{\'e}dric Duret and Edith Raulet and F. Casaus Navarro and Pierre Blanc and J. L. Cruz Ramos and Patrick Maurel and Martine Daujat-Chavanieu},
  journal={Methods in molecular biology},
  year={2010},
  volume={640},
  pages={
          247-60
        }
}
Highly differentiated normal human hepatocytes represent the gold standard cellular model for basic and applied research in liver physiopathology, pharmacology, toxicology, virology, and liver biotherapy. Nowadays, although livers from organ donors or medically required resections represent the current sources of hepatocytes, the possibility to generate hepatocytes from the differentiation of adult and embryonic stem cells represents a promising opportunity. The aim of this chapter is to… CONTINUE READING
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