Isolation and confirmation of the proposed cleistanthol biogentic link from Croton insularis.

@article{Maslovskaya2011IsolationAC,
  title={Isolation and confirmation of the proposed cleistanthol biogentic link from Croton insularis.},
  author={Lidia A Maslovskaya and Andrei Savchenko and Victoria A. Gordon and Paul W. Reddell and Carly J. Pierce and Peter G Parsons and Craig M Williams},
  journal={Organic letters},
  year={2011},
  volume={13 5},
  pages={1032-5}
}
The proposed cleistanthol biosynthetic intermediate en route to spruceanol, and other related family members, was isolated for the first time from Croton insularis, confirming the Jacobs-Reynolds hypothesis. Anticancer evaluation of the new isolates and their aerial oxidation products is also reported.