Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene.

@article{Schwidetzky1995IsolationAC,
  title={Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene.},
  author={Uta Schwidetzky and W D Schleuning and Bernard Haendler},
  journal={The Biochemical journal},
  year={1995},
  volume={321 ( Pt 2)},
  pages={
          325-32
        }
}
In mice, cysteine-rich secretory protein-1 (CRISP-1) is mainly found in the epididymis and also, to a lesser extent, in the salivary gland of males, where androgens control its expression. We have now isolated and characterized overlapping phage clones covering the entire length of the CRISP-1 gene. DNA sequencing revealed that the gene is organized into eight exons, ranging between 55 and 748 bp in size, and seven introns. All exon-intron junctions conformed to the GT/AG rule established for… CONTINUE READING

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