Isolation and characterization of the Beadex locus of Drosophila melanogaster: a putative cis-acting negative regulatory element for the heldup-a gene.

@article{Mattox1984IsolationAC,
  title={Isolation and characterization of the Beadex locus of Drosophila melanogaster: a putative cis-acting negative regulatory element for the heldup-a gene.},
  author={William W. Mattox and Norman Davidson},
  journal={Molecular and cellular biology},
  year={1984},
  volume={4 7},
  pages={1343-53}
}
We isolated recombinant lambda phage clones spanning 49 kilobases of DNA which contain the Beadex and heldup-a loci of Drosophila melanogaster. These cloned DNAs were used to analyze the structure of eight dominant mutant alleles of the Beadex locus which show increased gene activity. A region, only 700 base pairs in length, is altered in each of these mutants. Six of the mutations have DNA insertions within this segment. Most of these insertions resemble retrovirus-like transposable elements… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 37 references

A comparison of mutation rates for specific loci and chromosome regions in dysgenic hybrid males of Drosophila melanogaster

R. F. Smith
Genetics • 1984

Isolation of the Drosophila melanogaster dunce chromosomal region and recombinational mapping of dunce sequences with restriction site polymorphisms as genetic markers

L Davis.R., N. Davidson
Mol . Cell . Biol . • 1984
View 1 Excerpt

Similar Papers

Loading similar papers…