Isolation and characterization of rad51 orthologs from Coprinus cinereus and Lycopersicon esculentum, and phylogenetic analysis of eukaryotic recA homologs

@article{Stassen1997IsolationAC,
  title={Isolation and characterization of rad51 orthologs from Coprinus cinereus and Lycopersicon esculentum, and phylogenetic analysis of eukaryotic recA homologs},
  author={Natalie Yeager Stassen and J. M. Logsdon Jr. and Gary J. Vora and Hildo H. Offenberg and Jeffrey D. Palmer and Miriam E. Zolan},
  journal={Current Genetics},
  year={1997},
  volume={31},
  pages={144-157}
}
Abstract In eubacteria, the recA gene has long been recognized as essential for homologous recombination and DNA repair. Recent work has identified recA homologs in archaebacteria and eukaryotes, thus emphasizing the universal role this gene plays in DNA metabolism. We have isolated and characterized two new recA homologs, one from the basidiomycete Coprinus cinereus and the other from the angiosperm Lycopersicon esculentum. Like the RAD51 gene of Saccharomyces cerevisiae, the Coprinus gene is… 

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TLDR
The results suggest that endosymbiotic transfer of recA genes occurred from mitochondria and chloroplasts to nuclear genomes of ancestral eukaryotes.

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TLDR
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Reevaluation of the evolutionary events within recA/RAD51 phylogeny

TLDR
A robust, parsimonious and more refined phylogenetic history of the recA/RAD51 superfamily is obtained, which provides a better understanding of the ancient origin of recA proteins and the multiple events that lead to the diversification ofRecA homologs in eukaryotes, including the discovery of additional RAD51 sub-families.

Isolation, characterisation and expression patterns of a RAD51 ortholog from Pleurotus ostreatus

TLDR
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Extraction of Deep Phylogenetic Signal and Improved Resolution of Evolutionary Events within the recA/RAD51 Phylogeny

TLDR
A robust, parsimonious and more refined phylogenetic history of the recA/RAD51 superfamily is obtained, which provides a better understanding of ancient origin of recA proteins and multiple events leading to the diversification ofRecA homologs in eukaryotes, including the discovery of additional RAD51 sub-families.

Analysis of the Basidiomycete Coprinopsis cinerea Reveals Conservation of the Core Meiotic Expression Program over Half a Billion Years of Evolution

TLDR
It is found that meiotic genes are significantly more conserved in their transcript profiles than genes not known to be meiotic, which indicates a remarkable conservation of the meiotic process across evolutionarily distant organisms.

Isolation and characterisation of the RAD51 and DMC1 homologs from Arabidopsis thaliana

TLDR
The isolation of two genes belonging to the RAD51 and DMC1 families from Arabidopsis thaliana indicated that not only AtRAD51 but also AtDMC1 are regulated during the cell cycle, with S-phase-specific induction.

Molecular analysis of pcc1, a gene that leads to A-regulated sexual morphogenesis in Coprinus cinereus.

TLDR
Genetic analysis showed that the formation of pseudoclamps results from a recessive mutation in a gene designated pcc1 (pseudoclamp connection formation), which is distinct from the A and B mating type genes.

An mre11 mutant of Coprinus cinereus has defects in meiotic chromosome pairing, condensation and synapsis.

TLDR
The rad11 gene of the basidiomycete Coprinus cinereus is cloned and shown that it is a homolog of MRE11, a gene required for meiosis and DNA repair in numerous organisms, and in C. cinreus, Mre11 is necessary for meiotic DNA metabolism.
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