Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells.

Abstract

The neural crest is a transient structure of vertebrate embryos that initially generates neural crest stem cells (NCSCs) which then migrate throughout the body to produce a diverse array of mature tissue types. Due to the rarity of adult NCSCs as well as ethical and technical issues surrounding isolation of early embryonic tissues, biologic studies of human… (More)
DOI: 10.1089/scd.2008.0362

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