Isolation and characterization of monoclonal antibodies specific for antigen P1, a major surface protein of mutans streptococci.

@article{Ayakawa1987IsolationAC,
  title={Isolation and characterization of monoclonal antibodies specific for antigen P1, a major surface protein of mutans streptococci.},
  author={G Y Ayakawa and L W Boushell and Paula J. Crowley and Gregory W. Erdos and William P. McArthur and Arnold S. Bleiweis},
  journal={Infection and immunity},
  year={1987},
  volume={55 11},
  pages={2759-67}
}
A panel of 15 murine monoclonal antibodies (MAbs; 14 immunoglobulin G1, 1 immunoglobulin G2a) directed against antigen P1, a major surface protein of mutans streptococci, was prepared. All of these MAbs reacted by the enzyme-linked immunosorbent assay with solubilized wall material from Streptococcus mutans Ingbritt 175 (a serotype c strain which retains significant amounts of P1 in its cell wall), culture supernatant fluid from Ingbritt 162 (a strain which excretes large amounts of P1 into the… CONTINUE READING
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