Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells.

Abstract

Down-regulation of immune responses by regulatory T (Treg) cells is an important mechanism involved in the induction of tolerance to allo-antigens (Ags). Recently, a novel subset of Ag-specific T-cell receptor (TCR)alpha beta+ CD4(-)CD8- (double-negative [DN]) Treg cells has been found to be able to prevent the rejection of skin and heart allografts by… (More)

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Cite this paper

@article{Fischer2005IsolationAC, title={Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells.}, author={Karin Fischer and Simon Voelkl and Jana Heymann and Grzegorz Krzysztof Przybylski and Krishna Mondal and Monika Laumer and Leoni A. Kunz-Schughart and Christian A. Schmidt and Reinhard Andreesen and Andreas Mackensen}, journal={Blood}, year={2005}, volume={105 7}, pages={2828-35} }