Isolation and characterization of highly radioresistant malignant hamster fibroblasts that survive acute gamma irradiation with 20 Gy.

Abstract

To study the acquired radioresistance of tumor cells, a model system of two cell lines, Djungarian hamster fibroblasts (DH-TK-) and their radioresistant progeny, was established. The progeny of irradiated cells were isolated by treating the parental cell monolayer with a single dose of 20 Gy (PIC-20). The genetic and morphological features, clonogenic… (More)

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@article{Tyrsina2005IsolationAC, title={Isolation and characterization of highly radioresistant malignant hamster fibroblasts that survive acute gamma irradiation with 20 Gy.}, author={Ekaterina G Tyrsina and Svetlana V Slanina and Evgeniya S Kakpakova and Galina S. Kalendo and Natalia G. Kan and Oleg Yu. Tyrsin and Alexei Petrovich Ryskov}, journal={Radiation research}, year={2005}, volume={164 6}, pages={745-54} }