Isolation and characterization of endophytic huperzine A-producing fungi from Huperzia serrata

  title={Isolation and characterization of endophytic huperzine A-producing fungi from Huperzia serrata},
  author={Ya Wang and Qing Gui Zeng and Zhi Bin Zhang and Ri Ming Yan and Ling Yun Wang and Du Zhu},
  journal={Journal of Industrial Microbiology & Biotechnology},
Huperzia serrata is a producer of huperzine A (HupA), a cholinesterase inhibitor (ChEI). Over 120 endophytic fungi were recovered from this plant and screened for Hup-A and nine were found. These nine represented seven different fungal genera with the most significant producer being Shiraia sp. A total of 127 endophytic fungi isolates obtained from the root, stem, and leaf segments of H. serrata were grouped into 19 genera based on their morphological traits and sequence analysis of the… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 12 extracted citations


Publications referenced by this paper.
Showing 1-10 of 51 references

a new method for reconstructing phylogenetic trees

N Saitou, Nei M The neighbor-joining method
Mol Biol Evol 4:406–425 J Ind Microbiol Biotechnol • 2011
View 1 Excerpt

Endophytic fungus Cladosporium cladosporioides LF70 from Huperzia serrata produces Huperzine A

ZB Zhang, QG Zeng, +3 authors D Zhu
World J Microbiol Biotechnol • 2010
View 2 Excerpts

Molecular identification of endophytic fungi from medicinal plant Huperzia serrata based on rDNA ITS analysis

XY Chen, YD Qi, +4 authors BC Gan
World J Microbiol Biotechnol • 2010

Isolation and preliminary identification of the endophytic fungi which produce Hupzine A from four species in Hupziaceae and determination of huperzine A by HPLC

Z Ju, J Wang, SL Pan
FEMS Immunol Med Microbiol • 2009
View 2 Excerpts

Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia

DO Guimaraes, WS Borges, +7 authors MT Pupo
FEMS Immunol. Med Microbiol • 2008

Similar Papers

Loading similar papers…