Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas.

@article{Rovira2010IsolationAC,
  title={Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas.},
  author={Meritxell Rovira and Sherri-Gae Scott and Andrew S Liss and Jan Jensen and Sarah P. Thayer and Steven D. Leach},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 1},
  pages={75-80}
}
The question of whether dedicated progenitor cells exist in adult vertebrate pancreas remains controversial. Centroacinar cells and terminal duct (CA/TD) cells lie at the junction between peripheral acinar cells and the adjacent ductal epithelium, and are frequently included among cell types proposed as candidate pancreatic progenitors. However these cells have not previously been isolated in a manner that allows formal assessment of their progenitor capacities. We have found that a subset of… CONTINUE READING

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