Isolation and characterization of cytotoxic cyclotides from Viola tricolor

@article{Tang2010IsolationAC,
  title={Isolation and characterization of cytotoxic cyclotides from Viola tricolor},
  author={J. Tang and C. K. Wang and Xulin Pan and H. Yan and Ninghua Tan},
  journal={Peptides},
  year={2010},
  volume={31},
  pages={1434-1440}
}
  • J. Tang, C. K. Wang, +2 authors Ninghua Tan
  • Published 2010
  • Biology, Medicine
  • Peptides
  • Many plants of the Violaceae plant family have been used in traditional remedies, and these plants often contain cyclotides, a particular type of plant cyclopeptide that is distinguished by a cyclic cystine knot motif. In general, bioactive plant cyclopeptides are interesting candidates for drug development. In the current study, a suite of 14 cyclotides, which includes seven novel cyclotides [vitri B, C, D, E, F, varv Hm, and He], together with seven known cyclotides [varv A, D, E, F, H, vitri… CONTINUE READING

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