Isolation and characterization of butanol-resistant mutants of Clostridium acetobutylicum.

@article{Hermann1985IsolationAC,
  title={Isolation and characterization of butanol-resistant mutants of Clostridium acetobutylicum.},
  author={Marcela Hermann and Françoise Fayolle and R{\'e}my Marchal and Laurence Podvin and Madeleine Sebald and J. P. Vandecasteele},
  journal={Applied and environmental microbiology},
  year={1985},
  volume={50 5},
  pages={
          1238-43
        }
}
In a wild-type strain of Clostridium acetobutylicum isolated from soil, solvent production appeared limited by butanol toxicity. Butanol-resistant mutants have been obtained which produced significantly higher solvent concentrations (about 30%) than the wild-type strain. Some other physiological differences were observed between a selected resistant mutant and the wild-type strain at the level of solvent resistance and sporulation. 

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