Isolation and characterization of bleomycin-sensitive Chinese hamster ovary cells.

Abstract

Nineteen bleomycin-sensitive Chinese hamster ovary cell mutants have been isolated using a replica plating and photography approach. As judged by the dose which reduces cell survival to 37% of the untreated control, these mutants are from 2.5- to 32-fold more sensitive to a 16-h bleomycin treatment than the parental cell, while for chronic bleomycin… (More)

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Cite this paper

@article{Stamato1987IsolationAC, title={Isolation and characterization of bleomycin-sensitive Chinese hamster ovary cells.}, author={Thomas D. Stamato and Bjoern Peters and P. Patil and Nicholas C. Denko and Robert Weinstein and Amato J. Giaccia}, journal={Cancer research}, year={1987}, volume={47 6}, pages={1588-92} }