Isolation and characterization of biologically active and inactive cholecystokinin-octapeptides from human brain.

Abstract

Cholecystokinin-like immunoreactivity (CCK-LI) in 0.9 kg human brain was extracted by 2% trifluoroacetic acid at 4 degrees C. Sephadex G50 gel filtration of crude extract revealed one main molecular form of CCK, detected by a carboxy-terminal antibody (5135), that eluted in the position of CCK8. When the CCK-LI in the extract was purified by affinity… (More)

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@article{Reeve1984IsolationAC, title={Isolation and characterization of biologically active and inactive cholecystokinin-octapeptides from human brain.}, author={Joseph R. Reeve and Viktor Ernst Eysselein and J. H. Tull Walsh and Hariharan Sankaran and Clifford W. Deveney and Wallace W. Tourtellotte and Charles G. Miller and John E. Shively}, journal={Peptides}, year={1984}, volume={5 5}, pages={959-66} }