Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells.

@article{Shah2016IsolationAC,
  title={Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells.},
  author={A. M. Shah and A. Wani and Parvaiz H. Qazi and Shakeel-u Rehman and S. Mushtaq and Shiekh Abid Ali and A. Hussain and A. Shah and A. Qazi and Ubaid Makhdoomi and Abid Hamid and A. Kumar},
  journal={Chemico-biological interactions},
  year={2016},
  volume={256},
  pages={
          198-208
        }
}
  • A. M. Shah, A. Wani, +9 authors A. Kumar
  • Published 2016
  • Biology, Medicine
  • Chemico-biological interactions
  • The ethyl acetate extract from the fermentation broth of an actinomycete strain, identified as Streptomyces scabrisporus isolated from soil of Kashmir Himalayas - India, exhibited significant cytotoxic activity against a panel of human cancer cell lines. The active fraction subjected to column chromatography led to the isolation of pharmacologically potent anticancer compound whose structure was established to be alborixin on the basis of spectral data analysis. The compound exhibited… CONTINUE READING
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