Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA

@article{Kedersha1986IsolationAC,
  title={Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA},
  author={Nancy L. Kedersha and Leonard H Rome},
  journal={The Journal of Cell Biology},
  year={1986},
  volume={103},
  pages={699 - 709}
}
Rat liver coated vesicle preparations were frequently found to contain small ovoid bodies, which resembled coated vesicles in morphology. We have purified these bodies to homogeneity using sucrose density gradients and preparative agarose gel electrophoresis. When negatively stained and viewed by electron microscopy, the purified structures display a very distinct and complex morphology, resembling the multiple arches which form cathedral vaults. They measure 35 X 65 nm and are therefore… CONTINUE READING
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RNA Sequencing. In Gel Electrophoresis of Nucleic Acids

  • J. M. D'Alessio
  • 1982

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