Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence.

@article{Jahn1997IsolationAC,
  title={Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence.},
  author={Bernhard Jahn and Andreas Koch and Axel Schmidt and Gerhard Wanner and Heike Gehringer and Sucharit Bhakdi and Axel A. Brakhage},
  journal={Infection and immunity},
  year={1997},
  volume={65 12},
  pages={5110-7}
}
Aspergillus fumigatus is an important pathogen of immunocompromised hosts, causing pneumonia and invasive disseminated disease with high mortality. The factors contributing to the predominance of A. fumigatus as an opportunistic pathogen are largely unknown. Since the survival of conidia in the host is a prerequisite for establishing disease, we have been attempting to identify factors which are associated with conidia and, simultaneously, important for infection. Therefore, an A. fumigatus… CONTINUE READING
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