Isolation and characterization of a cytotoxic metabolite of Talaromyces bacillosporus

@article{Ishii1995IsolationAC,
  title={Isolation and characterization of a cytotoxic metabolite of Talaromyces bacillosporus},
  author={Kenji Ishii and T Itoh and K. Kobayashi and Y Horie and Yoshio Ueno},
  journal={Applied and Environmental Microbiology},
  year={1995},
  volume={61},
  pages={941 - 943}
}
  • K. Ishii, T. Itoh, Y. Ueno
  • Published 1 March 1995
  • Biology, Chemistry
  • Applied and Environmental Microbiology
A cytotoxic metabolite, talarotoxin, was isolated from a fungus, Talaromyces bacillosporus IFO 8397, cultured on rice. The structure of the toxin was elucidated and found to contain a pyrrolizidinedione connected with a trans delta 1-octalin through a conjugated triene. 
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