Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3.

@article{McCoubrey1997IsolationAC,
  title={Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3.},
  author={William McCoubrey and Tsung J Huang and Mahin D. Maines},
  journal={European journal of biochemistry},
  year={1997},
  volume={247 2},
  pages={725-32}
}
Two isozymes of heme oxygenase (HO), HO-1 or HSP32 and the constitutive form HO-2, have been characterized to date. We report the discovery of a third protein species and refer to it as HO-3. HO-3 is the product of a single transcript of approximately 2.4 kb and can encode a protein of approximately 33 kDa. The HO-3 transcript is found in the spleen, liver, thymus, prostate, heart, kidney, brain and testis and is the product of a single-copy gene. The predicted amino acid structure of HO-3… CONTINUE READING