Isolation and characterization of a 92-KD surface molecule of Trypanosoma cruzi amastigotes recognized by a monoclonal antibody that induces complement-mediated killing.

Abstract

The presence of lytic antibodies in the circulation of patients with chronic Chagas' disease might lead to their cure. It has been shown that amastigotes of Trypanosoma cruzi activate complement and accumulate large amounts of the terminal complement components, but without killing the parasites. One plausible explanation for this observation is that the… (More)

Topics

Cite this paper

@article{Iida1991IsolationAC, title={Isolation and characterization of a 92-KD surface molecule of Trypanosoma cruzi amastigotes recognized by a monoclonal antibody that induces complement-mediated killing.}, author={K. Iida and Victoria Ley}, journal={The American journal of tropical medicine and hygiene}, year={1991}, volume={45 5}, pages={619-28} }