Isolation and characterization of Tula virus, a distinct serotype in the genus Hantavirus, family Bunyaviridae.

@article{Vapalahti1996IsolationAC,
  title={Isolation and characterization of Tula virus, a distinct serotype in the genus Hantavirus, family Bunyaviridae.},
  author={Olli Vapalahti and {\AA}ke Lundkvist and Sami K. J. Kukkonen and Yangjian Cheng and Marita Gilljam and Mari Kanerva and Tytti Manni and Milan Pej{\vc}och and Jukka Niemimaa and A Kaikusalo and Heikki Henttonen and Antti Vaheri and Alexander Plyusnin},
  journal={The Journal of general virology},
  year={1996},
  volume={77 ( Pt 12)},
  pages={3063-7}
}
A Vero E6 cell culture isolate of Tula virus (TUL), a hantavirus first detected in European common voles (Microtus arvalis and M. rossiaemeridionalis) by RT-PCR was obtained after initial passaging of TUL-infected vole lung samples in laboratory-colonized M. arvalis. TUL was defined as a classical serotype by a cross-focus-reduction neutralization test (FRNT) and was also shown to be distinct from other hantaviruses by haemagglutination inhibition assay. The sequences of S, M and partial L… CONTINUE READING
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