Isolation and characterization of DNA from archaeological bone

@article{Hagelberg1991IsolationAC,
  title={Isolation and characterization of DNA from archaeological bone},
  author={Erika Hagelberg and John Brian Clegg},
  journal={Proceedings of the Royal Society of London. Series B: Biological Sciences},
  year={1991},
  volume={244},
  pages={45 - 50}
}
  • E. HagelbergJ. Clegg
  • Published 22 April 1991
  • Biology
  • Proceedings of the Royal Society of London. Series B: Biological Sciences
Key MethodDNA was extracted from human and animal bones recovered from archaeological sites and mitochondrial DNA sequences were amplified from the extracts using the polymerase chain reaction. Evidence is presented that the amplified sequences are authentic and do not represent contamination by extraneous DNA. The results show that significant amounts of genetic information can survive for long periods in bone, and have important implications for evolutionary genetics, anthropology and forensic science.

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