Isolation and characterisation of four cDNAs encoding neuromedin U (NMU) from the brain and gut of goldfish, and the inhibitory effect of a deduced NMU on food intake and locomotor activity.

@article{Maruyama2008IsolationAC,
  title={Isolation and characterisation of four cDNAs encoding neuromedin U (NMU) from the brain and gut of goldfish, and the inhibitory effect of a deduced NMU on food intake and locomotor activity.},
  author={Katsuya Maruyama and Norifumi Konno and Koich Ishiguro and Tatsuya Wakasugi and Minoru Uchiyama and Seiji Shioda and K Matsuda},
  journal={Journal of neuroendocrinology},
  year={2008},
  volume={20 1},
  pages={71-8}
}
In rodents, neuromedin U (NMU; U for its original effects examined in the uterus) is a multifunctional neuropeptide implicated in the regulation of the circulatory and digestive systems and energy homeostasis, especially appetite. However, there is no available information on the nature and physiological roles of NMU in fish. Therefore, we attempted to isolate and characterise transcripts encoding NMU from the brain and gut of the goldfish, and to examine the involvement of NMU in the… CONTINUE READING