Isolation and biological characterization of neurotoxic compounds from the sea anemone Lebrunia danae (Duchassaing and Michelotti, 1860)

@article{SnchezRodrguez2006IsolationAB,
  title={Isolation and biological characterization of neurotoxic compounds from the sea anemone Lebrunia danae (Duchassaing and Michelotti, 1860)},
  author={Judith S{\'a}nchez-Rodr{\'i}guez and Karina Cruz-Vazquez},
  journal={Archives of Toxicology},
  year={2006},
  volume={80},
  pages={436-441}
}
This paper describes two neurotoxic proteins obtained from the Caribbean sea anemone Lebrunia danae. To assess the neurotoxic activity of the venom of L. danae, several bioassays were carried out, and to evaluate the effect of the toxin, Median Lethal Doses (LD50) were determined in vivo using sea crabs (Ocypode quadrata) and Artemia salina nauplii with the crude extract of the proportion of 2.82 mg/m. The proteins with neurotoxic effects were isolated using low-pressure liquid chromatography… CONTINUE READING