Isolation, sequencing and expression of Bartonella henselae omp43 and predicted membrane topology of the deduced protein.

@article{Burgess2000IsolationSA,
  title={Isolation, sequencing and expression of Bartonella henselae omp43 and predicted membrane topology of the deduced protein.},
  author={Anthony W. Burgess and J Y Paquet and J J Letesson and Burt E. Anderson},
  journal={Microbial pathogenesis},
  year={2000},
  volume={29 2},
  pages={73-80}
}
The infection of and interaction of human endothelial cells with Bartonella henselae is one of the most interesting aspects of Bartonella -associated disease. The gene encoding the 43 kDa B. henselae outer membrane protein (Omp43) that binds endothelial cells was cloned and sequenced. Sequence analysis revealed an open reading frame of 1206 nucleotides coding for a protein of 402 amino acids. Analysis of the deduced amino acid sequence shows 38% identity over the entire sequence to the Brucella… CONTINUE READING