Isolation, purification, and cross-linking profiles of elastin from lung and aorta.

@article{Paz1976IsolationPA,
  title={Isolation, purification, and cross-linking profiles of elastin from lung and aorta.},
  author={Mercedes A. Paz and David A. Keith and Hector Pedro Traverso and Paul M. Gallop},
  journal={Biochemistry},
  year={1976},
  volume={15 22},
  pages={4912-8}
}
Elastin from anatomically defined regions of young calf lung and dog aorta was isolated and purified by a procedure which sequentially removed lipids, collagen, structural glycoproteins, and the microfibrillar proteins without apparent damage to the cross-linking residues, which have been shown to be sensitive to autoclaving and hot alkali treatment. One of the methods described was effective in obtaining pure elastin from lung parenchyma. Visceral pleura was found to be the richest source (25… CONTINUE READING