Isolation, properties, and androgen regulation of a 20-kilodalton protein from rat ventral prostate.


An abundant 20-kilodalton protein has been isolated from the cytosol fraction of rat ventral prostate by ammonium sulfate precipitation, DNA-cellulose chromatography, and gel filtration. The purified 20K protein is a glycoprotein, containing 11% hexose by weight. It contains no fucose, hexosamine, or sialic acid. The 20K protein does not bind androgen… (More)


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