Isolation, functional, and partial biochemical characterization of galatrox, an acidic lectin from Bothrops atrox snake venom.

@article{MendonaFranqueiro2011IsolationFA,
  title={Isolation, functional, and partial biochemical characterization of galatrox, an acidic lectin from Bothrops atrox snake venom.},
  author={Elaine de Paula Mendonça-Franqueiro and Raquel de Melo Alves-Paiva and Marco Aur{\'e}lio Sartim and Daniel Roberto Callejon and Helder Henrique Paiva and Gilmara Ausech Antonucci and Jos{\'e} C{\'e}sar Rosa and Ad{\'e}lia Cristina Oliveira Cintra and Jo{\~a}o Jos{\'e} Franco and Eliane C Arantes and Marcelo Dias-Baruffi and Suely Vilela Sampaio},
  journal={Acta biochimica et biophysica Sinica},
  year={2011},
  volume={43 3},
  pages={181-92}
}
Snake venom lectins have been studied in regard to their chemical structure and biological functions. However, little is known about lectins isolated from Bothrops atrox snake venom. We report here the isolation and partial functional and biochemical characterization of an acidic glycan-binding protein called galatrox from this venom. This lectin was purified by affinity chromatography using a lactosyl-sepharose column, and its homogeneity and molecular mass were evaluated by high-performance… CONTINUE READING
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