Isolation, electron microscopy and 3D reconstruction of invertebrate muscle myofilaments.

@article{Craig2012IsolationEM,
  title={Isolation, electron microscopy and 3D reconstruction of invertebrate muscle myofilaments.},
  author={Roger Craig},
  journal={Methods},
  year={2012},
  volume={56 1},
  pages={33-43}
}
Understanding the molecular mechanism of muscle contraction and its regulation has been greatly influenced and aided by studies of myofilament structure in invertebrate muscles. Invertebrates are easily obtained and cover a broad spectrum of species and functional specializations. The thick (myosin-containing) filaments from some invertebrates are especially stable and simple in structure and thus much more amenable to structural analysis than those of vertebrates. Comparative studies of… CONTINUE READING
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