Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt.


The region-specific homeotic gene spalt (sal) of Drosophila specifies head and tail as opposed to trunk segments. During later stages of ontogenesis, sal is also expressed and required in a small number of tissues and organs in the developing embryo. sal encodes a zinc finger protein of unusual but characteristic structure. We made use of these unique… (More)