Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells.

@article{Majumdar2000IsolationCA,
  title={Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells.},
  author={Manas K. Majumdar and Veronica Banks and Diane Peluso and Elisabeth A. Morris},
  journal={Journal of cellular physiology},
  year={2000},
  volume={185 1},
  pages={98-106}
}
Multipotential bone marrow stromal cells have the ability to differentiate along multiple connective tissue lineages including cartilage. In this study, we developed an efficient and reproducible procedure for the isolation of stromal cells from bone marrow aspirates of normal human donors based on the expression of endoglin, a type III receptor of the transforming growth factor-beta (TGF-beta) receptor family. We demonstrate that these cells have the ability of multiple lineage differentiation… CONTINUE READING

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