Isolating intrinsic noise sources in a stochastic genetic switch.

@article{Newby2012IsolatingIN,
  title={Isolating intrinsic noise sources in a stochastic genetic switch.},
  author={Jay M. Newby},
  journal={Physical biology},
  year={2012},
  volume={9 2},
  pages={026002}
}
The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule that binds to the promotor of the other gene. When the repressor is bound to a promotor, the corresponding gene is not transcribed and no protein is produced. Either one of the promotors can be repressed at any given time or both can be unrepressed, leaving… CONTINUE READING
Highly Cited
This paper has 23 citations. REVIEW CITATIONS

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Newby and James P . Keener . An asymptotic analysis of the spatially inhomogeneous velocity - jump process

M. Jay
Phys . Rev . E • 2011

Perturbation analysis of spontaneous action potential initiation by stochastic ion channels.

Physical review. E, Statistical, nonlinear, and soft matter physics • 2011
View 2 Excerpts

Elowitz . Functional roles for noise in genetic circuits

Avigdor Eldar, B Michael
Nature • 2010

Keener and Jay M . Newby . Perturbation analysis of spontaneous action potential initiation by stochastic ion channels

P. James
J . Math . Biol . • 2010

Metastable states and quasicycles in a stochastic Wilson-Cowan model of neuronal population dynamics.

Physical review. E, Statistical, nonlinear, and soft matter physics • 2010
View 1 Excerpt

Theory and applications of stochastic processes: an analytical approach, volume v. 170 of Applied mathematical sciences

Zeev Schuss
2010
View 3 Excerpts

Similar Papers

Loading similar papers…