Isolated systolic hypertension in the elderly

@article{Chobanian2007IsolatedSH,
  title={Isolated systolic hypertension in the elderly},
  author={Aram V. Chobanian},
  journal={The New England Journal of Medicine},
  year={2007},
  volume={357},
  pages={789-796}
}
  • A. Chobanian
  • Published 23 August 2007
  • Medicine
  • The New England Journal of Medicine
Key MethodA 68-year-old accountant visits his physician. A year earlier he was told that his blood pressure was somewhat elevated and was advised to reduce salt intake and increase activity. Otherwise, he has been in good health and has no history or signs of cardiovascular or renal disease. On physical examination, his blood pressure is 178/72 mm Hg, and his body-mass index is 28.4. How should he be further evaluated and treated?
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Background Citations
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105 Citations

HYPERTENSION IN ELDERLY:OUR CURRENT TRENDS

A literature review of trials published in English in the last 10 years designed to study the effectiveness and safety of various BP targets in patients who are 70 years or older found that the benets in the positive studies were demonstrated even with a minimal BPcontrol and continued to be reported for a SBP<120 mmHg.

Hypertension Management in the Elderly: What is the Optimal Target Blood Pressure?

A literature review of trials published in English in the last 10 years designed to study the efficacy and safety of various BP targets in patients who are 70 years or older found that the benefits in the positive studies were demonstrated even with a minimal BP control and continued to be reported for a SBP <120 mmHg.

General principles of hypertension management in the elderly.

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Isolated systolic hypertension in very elderly

Systolic blood pressure (BP) is more important in predicting adverse cerebrovascular outcomes and decline in renal function in elderly patients with ISH and early detection, protection of target organs, correction of high BP will develop, promote, and corroborate healthy aging.

Drug treatment of hypertension in older patients with diabetes mellitus

Clinicians should have a BP goal of less than 130/80 mm in all elderly patients with hypertension and DM, especially in those with high CV-risk, and when medications are required for optimal BP control in addition to lifestyle measures, either thiazide diuretics, angiotensin-converting-enzyme inhibitors, ang Elliotensin receptor blockers, or calcium channel blockers should be considered as initial therapy.

Age-differential association between serum uric acid and incident hypertension

An age-differential association between SUA level and incident hypertension among Koreans is observed, which can be a trigger for hypertension through early vascular changes in the middle-aged population.

Older Women with Controlled Isolated Systolic Hypertension: Exercise and Blood Pressure.

Despite being well controlled and normotensive control subjects at rest, ISH patients had high SBP responses to both dynamic and static exercises, which may constitute a risk for cardiovascular incidents.

Treatment strategies for isolated systolic hypertension in elderly patients

The authors systematically review published studies to appraise the scientific and clinical evidence supporting the role of blood pressure control in elderly patients with isolated systolic hypertension, and to assess the influence of different drug treatment regimens on outcomes.

Angiotensin II type 1 receptor antagonists in the treatment of hypertension in elderly patients: focus on patient outcomes

AT1 receptor antagonists represent an appropriate option for many elderly patients with hypertension, type 2 diabetes, heart failure, and/or left ventricular dysfunction, including potential for improved adherence, excellent tolerability profile with minimal first-dose hypotension, and a low incidence of adverse effects.
...

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