Isolated rat cortical progenitor cells are maintained in division in vitro by membrane-associated factors.

@article{Temple1994IsolatedRC,
  title={Isolated rat cortical progenitor cells are maintained in division in vitro by membrane-associated factors.},
  author={Sally Temple and Andrew A. Davis},
  journal={Development},
  year={1994},
  volume={120 4},
  pages={999-1008}
}
Ventricular zone cells in the developing CNS undergo extensive cell division in vivo and under certain conditions in vitro. The culture conditions that promote cell division have been studied to determine the role that contact with cell membrane associated factors play in the proliferation of these cells. Progenitor cells have been taken from the ventricular zone of developing rat cerebral cortex and placed into microwells. Small clusters of these cells can generate large numbers of neurons and… CONTINUE READING