Isolated lytic bone lesion as extramedullary disease in chronic myelogenous leukemia: a report of three new cases.

@article{Maloisel2005IsolatedLB,
  title={Isolated lytic bone lesion as extramedullary disease in chronic myelogenous leukemia: a report of three new cases.},
  author={F r{\'e}d{\'e}ric Maloisel and Guillaume Favre and Lahaucine Mahmal and Alina D Zamfir and Emmanuel Andres},
  journal={European journal of internal medicine},
  year={2005},
  volume={16 4},
  pages={288-90}
}
This short report describes three patients with chronic myeloid leukemia and isolated extramedullary bone disease with isolated lytic bone lesions. All these patients were in chronic phase when skeletal blast crisis took place. All the patients developed a full-blown blastic crisis within 3 months, with a rapidly fatal outcome, despite several intensive therapies. 

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