Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

@inproceedings{Toledo2010IsolatedFS,
  title={Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis},
  author={Rodrigo de Toledo and Berenice B Mendonca and Maria Candida B. V. Fragoso and Iber{\^e} Cauduro Soares and Madson Queiroz Almeida and Michelle B de Moraes and Delmar Muniz Lourenço and Ven{\^a}ncio A. F. Alves and M D Bronstein and Sergio P. A. Toledo},
  booktitle={Clinics},
  year={2010}
}
OBJECTIVE Non-pituitary tumors have been reported in a subset of patients harboring germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene. However, no detailed investigations of non-pituitary tumors of AIP-mutated patients have been reported so far. PATIENTS We examined a MEN1- and p53-negative mother-daughter pair with acromegaly due to somatotropinoma. Subsequently, the mother developed a large virilizing adrenocortical carcinoma and a grade II B-cell non… CONTINUE READING
Highly Cited
This paper has 51 citations. REVIEW CITATIONS
14 Citations
37 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

52 Citations

02040'12'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 52 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 37 references

The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas

  • CA Leontiou, M Gueorguiev, J van der Spuy, R Quinton, F Lolli, S Hassan
  • J Clin Endocrinol Metab
  • 2008
2 Excerpts

A ( ) Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas

  • T Iwata, S Yamada, N Mizusawa, HM Golam, T Sano, K Yoshimoto
  • J Clin Endocrinol Metab
  • 2007

Similar Papers

Loading similar papers…