Isolated central nervous system relapses in primary mediastinal large B-cell lymphoma after CHOP-like chemotherapy with or without Rituximab.

@article{Papageorgiou2013IsolatedCN,
  title={Isolated central nervous system relapses in primary mediastinal large B-cell lymphoma after CHOP-like chemotherapy with or without Rituximab.},
  author={Sotirios G Papageorgiou and Panayiotis Diamantopoulos and Georgia Levidou and Maria K Angelopoulou and Panagiota Economopoulou and Anna Efthimiou and Nikos Constantinou and Andreas Katsigiannis and Penelope Korkolopoulou and Vassiliki Pappa and Christina Economopoulou and George Georgiou and Maria Dimou and Panagiotis Tsirigotis and Marie-Christine Kyrtsonis and Ioannis Kotsianidis and Christina Kalpadakis and Meletios Athanasios Dimopoulos and Photis Beris and J. C. Meletis and Gerassimos Alexander Pangalis and J. G. Dervenoulas and Panayiotis P. Panayiotidis and Theodoros Vassilakopoulos},
  journal={Hematological oncology},
  year={2013},
  volume={31 1},
  pages={10-7}
}
Central nervous system (CNS) involvement in patients with primary mediastinal large B-cell (PMLBCL) lymphoma is a rare event, occurring in approximately 6% of patients, on the basis of the review of the literature prior to induction of Rituximab. The aim of this retrospective study was to describe the incidence of CNS relapse among 100 consecutive patients with PMLBCL who were treated with R-CHOP ± RT in comparison to patients treated with CHOP ± RT (n = 45) in 11 hospitals in Greece. Two… CONTINUE READING

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