Isolated Tumor Cells in the Sentinel Node Affect Long-Term Prognosis of Patients with Melanoma

@article{Scheri2007IsolatedTC,
  title={Isolated Tumor Cells in the Sentinel Node Affect Long-Term Prognosis of Patients with Melanoma},
  author={Randall P. Scheri and Richard Essner and Roderick R. Turner and MS XingYe and Donald L. Morton},
  journal={Annals of Surgical Oncology},
  year={2007},
  volume={14},
  pages={2861-2866}
}
The clinical significance of isolated tumor cells (ITCs) in the melanoma-draining sentinel nodes (SNs) is unclear. Records of patients who underwent SN biopsy (SNB) for stage I/II melanoma at our institute between 1991 and 2003 were reviewed to identify patients whose SNs were tumor-free or contained only ITC (≤0.2 mm). Tumor-positive SNs were reevaluated by the study pathologist to confirm the diagnosis and microstage the SN. Characteristics of the primary melanoma, tumor status of regional… CONTINUE READING

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