Isolate from the annelid, Reteterebella queenslandia (Australia), active against Ehrlich ascites tumor.

@article{Norton1973IsolateFT,
  title={Isolate from the annelid, Reteterebella queenslandia (Australia), active against Ehrlich ascites tumor.},
  author={T R Norton and Midori Kashiwagi and Ronald J. Quinn},
  journal={Journal of pharmaceutical sciences},
  year={1973},
  volume={62 9},
  pages={
          1464-8
        }
}
A fraction, isolated by dialysis and gel permeation chromatography from an aqueous ethanolic extract of the tentacles of Reteterebella queenslandia, controlled and cured Ehrlich ascites tumor in mice in microgram doses. It is effective by either intraperitoneal or subcutaneous injection. 
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Chapter 15. Antineoplastic Agents
Publisher Summary This chapter discusses the different aspects of antineoplastic agents. The antitumor agents are essentially inhibitors of cell growth, normal as well as tumor. The folate analogExpand

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Antitumor Activity in Mice of Tentacles of Two Tropical Sea Annelids
TLDR
Dialyzed extracts of one of these annelids, Lanice conchilega, show activity in the retentate after pronase digestion, suggesting that antitumor activity is associated with a nonprotein component of the crude tentacle extract. Expand
MERITS OF ASCITES TUMORS FOR CHEMOTHERAPEUTIC SCREENING
TLDR
The ascites tumors provide an easy challenge to chemotherapeutic agents, because the intraperitoneal injection of compounds against the intra peritoneal ascites form of tumors is easy to obtain an idea of the action of a compound without as great a degree of intervention by other organs. Expand