Isoflurane is an effective alternative to ketamine/xylazine/acepromazine as an anesthetic agent for the mouse electroretinogram

@article{Woodward2007IsofluraneIA,
  title={Isoflurane is an effective alternative to ketamine/xylazine/acepromazine as an anesthetic agent for the mouse electroretinogram},
  author={William R. Woodward and Dongseok Choi and J. D. Grose and B. Malmin and Sawan Hurst and Jiaqing Pang and Richard G. Weleber and D. M. Pillers},
  journal={Documenta Ophthalmologica},
  year={2007},
  volume={115},
  pages={187-201}
}
The electroretinogram (ERG) is an essential measure of retinal function for studying mouse models of retinal disease. Ketamine, in combination with xylazine and/or acepromazine, is the most commonly used anesthetic agent. Although it works well in most situations, some fragile mouse strains have high mortality rates with this ketamine cocktail. We compared isoflurane with the ketamine cocktail in a longitudinal study of light-adapted and dark-adapted ERGs in C57BL/6J mice. Waveforms were… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Effects of common anesthetics on eye movement and electroretinogram

  • Documenta Ophthalmologica
  • 2011
VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 29 REFERENCES

Age-related changes in the mouse outer retina.

  • Optometry and vision science : official publication of the American Academy of Optometry
  • 2001
VIEW 1 EXCERPT

Electrodiagnostic techniques for visual function testing in mice

S Nusinowitz, W Ridder, JR Heckenlively
  • 2001
VIEW 1 EXCERPT