Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs.

@article{Fujinaga2006IsofluraneIA,
  title={Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs.},
  author={Takuji Fujinaga and Takayuki Nakamura and Tatsuo Fukuse and Fengshi Chen and Jitian Zhang and Shugo Ueda and Hiroshi Hamakawa and Mitsugu Omasa and Hiroaki Sakai and Nobuharu Hanaoka and Hiromi Wada and Toru Bando},
  journal={Transplantation},
  year={2006},
  volume={82 9},
  pages={1168-74}
}
BACKGROUND Non-heart-beating donors are expected to ameliorate shortages of donors for organ transplantation. The issue of preventing warm ischemic injury after circulatory arrest must be investigated. In the current study, we investigated whether isoflurane inhalation during warm ischemia could attenuate ischemia reperfusion injury (IRI) of the lung. METHODS An isolated perfused rat lung model was used. The rats were allocated into four groups: the no ischemia group; the ischemia-1 minimum… CONTINUE READING

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