Isoflurane for refractory status epilepticus: a clinical series.

  title={Isoflurane for refractory status epilepticus: a clinical series.},
  author={W Andrew Kofke and Richard S K Young and Pamela H Davis and Susan K Woelfel and Lindsey Gray and David Johnson and Adrian Gelb and Rodney I Meeke and David Sjoquist Nick Warner and Kevin S. Pearson},
  volume={71 5},
General anesthesia has been recommended to control convulsive status epilepticus that is refractory to conventional anticonvulsant therapy. Halothane has been the recommended agent, but without experimental justification. Isoflurane, which has no reported organ toxicity and produces electrographic suppression at clinically useful concentrations in normal humans, should be a better volatile anesthetic for this purpose. The efficacy and safety of isoflurane administered to control convulsive… CONTINUE READING


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